Source: | Mouse | Gene Id: | 10059 |
Isotype: | IgG2b | Swiss Prot: | O00429 |
purity: | Affinity purification |
Background: |
This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms. |
Reactivity | Human |
Tested applications | WB IHC ELISA IP IF |
Clonality | Monoclonal Antibody |
Calculated MW | 80 kDa |
Recommended Dilutions |
WB 1:100-1:1000
IHC 1:50-1:500
IF 1:50-1:500
|
Immunogen | A recombinant protein of human DNM1L |
Storage | Store at 4°C in PBS with 0.1% gelatin and 0.1% sodium azide. Do not freeze. |
Synonym | DLP1, DRP1, DVLP, EMPF, DYMPLE, HDYNIV |
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