Species: | Mouse |
Applications: | WB IHC ELISA IP IF |
Immunogen Range: | A recombinant protein of human DNM1L |
Clonality: | Monoclonal Antibody |
Isotype: | IgG2b |
GENE ID: | 10059 |
Swiss Prot: | O00429 |
Synonyms: | DLP1, DRP1, DVLP, EMPF, DYMPLE, HDYNIV |
Purification: | Affinity purification |
Storage: | Store at 4°C in PBS with 0.1% gelatin and 0.1% sodium azide. Do not freeze. |
Background: | This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms. |
Caculated MW: | 80 kDa |
Observed MW: | Refer to Figures |
Applications: |
WB 1:100-1:1000 IHC 1:50-1:500 IF 1:50-1:500 |
Reacitivity: | Human |