AMM10059-51 [Monoclonal Antibody]
DNM1L Mouse Monoclonal Antibody
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Species:   Mouse
Applications:   WB IHC ELISA IP IF
Immunogen Range:   A recombinant protein of human DNM1L
Clonality:   Monoclonal Antibody
Isotype:   IgG2b
GENE ID:   10059
Swiss Prot:   O00429
Synonyms:   DLP1, DRP1, DVLP, EMPF, DYMPLE, HDYNIV
Purification:   Affinity purification
Storage:   Store at 4°C in PBS with 0.1% gelatin and 0.1% sodium azide. Do not freeze.
Background:   This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms.
Caculated MW:   80 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:100-1:1000
IHC 1:50-1:500
IF 1:50-1:500
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information