Source: | Mouse | Gene Id: | 699 |
Isotype: | IgG1 | Swiss Prot: | O43683 |
purity: | Affinity purification |
Background: |
This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants. |
Reactivity | Human |
Tested applications | WB ELISA IP IF |
Clonality | Monoclonal Antibody |
Calculated MW | 150 kDa |
Recommended Dilutions |
WB 1:100-1:1000
IF 1:50-1:500
|
Immunogen | A recombinant protein of human BUB1 |
Storage | Store at 4°C in PBS with 0.1% gelatin and 0.1% sodium azide. Do not freeze. |
Synonym | BUB1A, BUB1L, Hbub1 |
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