AMM699-51 [Monoclonal Antibody]
BUB1 Mouse Monoclonal Antibody
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Species:   Mouse
Applications:   WB ELISA IP IF
Immunogen Range:   A recombinant protein of human BUB1
Clonality:   Monoclonal Antibody
Isotype:   IgG1
GENE ID:   699
Swiss Prot:   O43683
Synonyms:   BUB1A, BUB1L, Hbub1
Purification:   Affinity purification
Storage:   Store at 4°C in PBS with 0.1% gelatin and 0.1% sodium azide. Do not freeze.
Background:   This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants.
Caculated MW:   150 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:100-1:1000
IF 1:50-1:500
Reacitivity:   Human
For research use only. Not intended for diagnostic or therapeutic use!
Additional information