| No | Size | Price | Availability | |
| MTM18613-51 | 50ul | 1500.00 | In Stock |  |
| MTM18613-51 | 100ul | 2000.00 | In Stock | |
| Source: | Rat | Gene Id: | 18613(Mouse) |
| Isotype: | IgG2a | Swiss Prot: | Q08481 |
| purity: | Affinity purification |
| Background: |
| Cell adhesion molecules are a family of closely related cell surface glycoproteins involved in cell-cell interactions during growth and are thought to play an important role in embryogenesis and development. Neuronal cell adhesion molecule (NCAM) expression is observed in a variety of human tumors including neuroblastomas, rhabdomyosarcomas, Wilms’ tumors, Ewing’s sarcomas and some primitive myeloid malignancies. The intracellular adhesion molecule-1 (ICAM-1), also referred to as CD54, is an integral membrane protein of the immunoglobulin superfamily and recognizes the ∫2/?1 and ∫2/?M integrins. PECAM-1 (platelet/endothelial cell adhesion molecule-1), also referred to as CD31, is a glycoprotein expressed on the cell surfaces of monocytes, neutrophils, platelets and a subpopulation of T cells. VCAM-1 (vascular cell adhesion molecule-1) was first identified as an adhesion molecule induced on human endothelial cells by inflammatory cytokines such as IL-1, tumor necrosis factor (TNF) and lipopolysaccharide (LPS). The KALIG gene encodes a nerve cell adhesion molecule (NCAM)-like protein and is deleted in 66% of patients with Kallmann’s syndrome, anosmia with secondary hypogonadism. |
| Reactivity | Mouse |
| Tested applications | WB IHC IP IF |
| Clonality | Monoclonal Antibody |
| Calculated MW | 130 kDa |
| Recommended Dilutions |
WB 1:100-1:1000
IHC 1:50-1:500
IF 1:50-1:500
|
| Immunogen | A mouse derived endothelioma cell line tEnd.1 |
| Storage | Store at 4°C in PBS with 0.1% gelatin and 0.1% sodium azide. Do not freeze. |
| Synonym | Cd31, Pecam, C85791, PECAM-1 |
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