MTM18613-51 [Monoclonal Antibody]
PECAM1 Rat Monoclonal Antibody
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Species:   Rat
Applications:   WB IHC IP IF
Immunogen Range:   A mouse derived endothelioma cell line tEnd.1
Clonality:   Monoclonal Antibody
Isotype:   IgG2a
GENE ID:   18613(Mouse)
Swiss Prot:   Q08481
Synonyms:   Cd31, Pecam, C85791, PECAM-1
Purification:   Affinity purification
Storage:   Store at 4°C in PBS with 0.1% gelatin and 0.1% sodium azide. Do not freeze.
Background:   Cell adhesion molecules are a family of closely related cell surface glycoproteins involved in cell-cell interactions during growth and are thought to play an important role in embryogenesis and development. Neuronal cell adhesion molecule (NCAM) expression is observed in a variety of human tumors including neuroblastomas, rhabdomyosarcomas, Wilms’ tumors, Ewing’s sarcomas and some primitive myeloid malignancies. The intracellular adhesion molecule-1 (ICAM-1), also referred to as CD54, is an integral membrane protein of the immunoglobulin superfamily and recognizes the ∫2/?1 and ∫2/?M integrins. PECAM-1 (platelet/endothelial cell adhesion molecule-1), also referred to as CD31, is a glycoprotein expressed on the cell surfaces of monocytes, neutrophils, platelets and a subpopulation of T cells. VCAM-1 (vascular cell adhesion molecule-1) was first identified as an adhesion molecule induced on human endothelial cells by inflammatory cytokines such as IL-1, tumor necrosis factor (TNF) and lipopolysaccharide (LPS). The KALIG gene encodes a nerve cell adhesion molecule (NCAM)-like protein and is deleted in 66% of patients with Kallmann’s syndrome, anosmia with secondary hypogonadism.
Caculated MW:   130 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:100-1:1000
IHC 1:50-1:500
IF 1:50-1:500
Reacitivity:   Mouse
For research use only. Not intended for diagnostic or therapeutic use!
Additional information