APP Mouse Monoclonal Antibody
No Size Price Availability  
AMM351-11 50ul 1500.00 In Stock
AMM351-11 100ul 2000.00 In Stock
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Source: Mouse Gene Id: 351
Isotype: IgG1 Swiss Prot: P05067
purity: Affinity purification
Background:
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq
Reactivity Human
Tested applications IHC
Clonality Monoclonal Antibody
Calculated MW 100-140 kDa
Recommended Dilutions
IHC 0.5-1 ug/mL
Immunogen A synthetic peptide (conjugated with KLH) corresponding to human Beta amyloid
Storage Store at -20°C on dry atmosphere.After reconstitution with 1 mL of 1.2% sodium acetate or neutral PBS and concentration will be 100 ug/mL, store at -20°C or lower.Avoid freeze/thaw cycles.
Synonym AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN2
This product is for research use only, not for diagnostic or therapeutic use!

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