Source: | Mouse | Gene Id: | 3630 |
Isotype: | IgG1 | Swiss Prot: | P01308 |
purity: | Affinity purification |
Background: |
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds. Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake. A variety of mutant alleles with changes in the coding region have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. [provided by RefSeq |
Reactivity | Human, Mouse, Rat |
Tested applications | IHC |
Clonality | Monoclonal Antibody |
Calculated MW | 6 kDa |
Recommended Dilutions |
IHC 0.4-1 ug/mL
|
Immunogen | Native purified human INS |
Storage | Store at -20°C on dry atmosphere.After reconstitution with 1 mL of 1.2% sodium acetate or neutral PBS and concentration will be 100 ug/mL, store at -20°C or lower.Avoid freeze/thaw cycles. |
Synonym | ILPR, IRDN, IDDM2, MODY10, Insulin |
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