Source: | Mouse | Gene Id: | 10313 |
Isotype: | IgG1 | Swiss Prot: | O95197 |
purity: | Affinity chromatography |
Background: |
RTN3, reticulon 3. The reticulons are a group of highly conserved genes with preferential expression in neuroendocrine tissues. RTN3 may be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. There are 5 isoforms. |
Reactivity | Human |
Tested applications | ELISA ICC |
Clonality | Monoclonal Antibody |
Calculated MW | 113 kDa |
Recommended Dilutions |
ICC 1:200-1:1000
|
Immunogen | A purified recombinant fragment of human RTN3 expressed in E. Coli |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | HAP, ASYIP, NSPL2, NSPLII, RTN3-A1 |
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