| No | Size | Price | Availability | |
| AMM846-51 | 50ul | 1500.00 | In Stock |  |
| AMM846-51 | 100ul | 2000.00 | In Stock | |
| Source: | Mouse | Gene Id: | 846 |
| Isotype: | IgG1 | Swiss Prot: | P41180 |
| purity: | Affinity purification |
| Background: |
| The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism. |
| Reactivity | Human, Mouse, Rabbit, Rat |
| Tested applications | WB IP IF |
| Clonality | Monoclonal Antibody |
| Calculated MW | 160 kDa |
| Recommended Dilutions |
WB 1:100-1:1000
IF 1:50-1:500
|
| Immunogen | A synthetic peptide corresponding to amino acids 15-29 in the extracelllular N-terminus of rat CASR |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | CAR, FHH, FIH, HHC, EIG8, HHC1, NSHPT, PCAR1, GPRC2A, HYPOC1 |
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