| No | Size | Price | Availability | |
| ARM999-24C | 50ul | 1500.00 | In Stock |  |
| ARM999-24C | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 999 |
| Isotype: | IgG | Swiss Prot: | P12830 |
| purity: | Affinity purification |
| Background: |
| This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq, Jul 2008] |
| Reactivity | Human, Mouse |
| Tested applications | FC |
| Clonality | Monoclonal Antibody |
| Calculated MW | 135 kDa |
| Recommended Dilutions |
FC 1:50
|
| Immunogen | A synthetic peptide corresponding to the sequence surrounding Pro780 of human E-cadherin protein |
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | Arc-1, CD324, CDHE, ECAD, LCAM, UVO |
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