| No | Size | Price | Availability | |
| ARMM016P-21 | 50ul | 1500.00 | In Stock |  |
| ARMM016P-21 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | / |
| Isotype: | IgG | Swiss Prot: | / |
| purity: | Affinity purification |
| Background: |
| Cyclin-dependent kinases (CDKs) are a family of Ser/Thr kinases that regulate cell-cycle transitions through their association and subsequent phosphorylation of targets in a strictly ordered fashion (1). The substrates for CDKs are proline-directed. The consensus amino acid sequence for CDK substrate is (K/R)(S*)PX(K/R), where X denotes any one of the 20 amino acids (2-4) and S* is the phosphorylation site. Phospho-(Ser) CDKs Substrate Antibody recognizes phosphorylated CDK substrates at their consensus motif, providing a powerful tool for CDK target discovery and characterization, as well as HTS drug screening for potential kinase regulators. |
| Reactivity | Human |
| Tested applications | WB IP |
| Clonality | Monoclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:1000
|
| Immunogen | A synthetic phospho-CDK substrate peptide library The antibody is formulated from two rabbit monoclones in order to cover a broad range of reactivity |
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | / |
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