| Source: | Rabbit | Gene Id: | 1965 | 
| Isotype: | IgG | Swiss Prot: | P05198 | 
| purity: | Affinity purification | 
| Background: | 
| The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S28), and the 52-kD EIF2-gamma subunit (EIF2S3). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha. | 
| Reactivity | Human, Monkey, Mouse, Rat | 
| Tested applications | WB | 
| Clonality | Monoclonal Antibody | 
| Calculated MW | 38 kDa | 
| Recommended Dilutions | WB 1:1000 | 
| Immunogen | A purified recombinant human eIF2α protein | 
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. | 
| Synonym | EIF2, EIF-2, EIF2A, EIF-2A, EIF-2alpha | 
沪ICP备15003525号    Copyright ©, 2013-2019, Yihyson All Rights Reserved. 