ARM1965-21C [Monoclonal Antibody]
EIF2S1 Rabbit Monoclonal Antibody (Biotinylated)
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Species:   Rabbit
Applications:   WB
Immunogen Range:   A purified recombinant human eIF2α protein
Clonality:   Monoclonal Antibody
Isotype:   IgG
GENE ID:   1965
Swiss Prot:   P05198
Synonyms:   EIF2, EIF-2, EIF2A, EIF-2A, EIF-2alpha
Purification:   Affinity purification
Storage:   Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles.
Background:   The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S28), and the 52-kD EIF2-gamma subunit (EIF2S3). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha.
Caculated MW:   38 kDa
Observed MW:   Refer to Figures
Applications:   WB 1:1000
Reacitivity:   Human, Monkey, Mouse, Rat
For research use only. Not intended for diagnostic or therapeutic use!
Additional information