INS Rabbit Monoclonal Antibody (Alexa Fluor(R) 488 Conjugate)
No Size Price Availability  
ARM3630-21C 50ul 1500.00 In Stock
ARM3630-21C 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 3630
Isotype: IgG Swiss Prot: P01308
purity: Affinity purification
Background:
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds. Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake. A variety of mutant alleles with changes in the coding region have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. [provided by RefSeq
Reactivity Human, Mouse, Rat
Tested applications IF FC
Clonality Monoclonal Antibody
Calculated MW 6 kDa
Recommended Dilutions
IF 1:200
FC 1:50
Immunogen A synthetic peptide corresponding to the sequence of human insulin
Storage Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles.
Synonym ILPR, IRDN, IDDM2, MODY10, Insulin
This product is for research use only, not for diagnostic or therapeutic use!

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