| Source: | Rabbit | Gene Id: | 3630 | 
| Isotype: | IgG | Swiss Prot: | P01308 | 
| purity: | Affinity purification | 
| Background: | 
| After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds. Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake. A variety of mutant alleles with changes in the coding region have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. [provided by RefSeq | 
| Reactivity | Human, Mouse, Rat | 
| Tested applications | IF FC | 
| Clonality | Monoclonal Antibody | 
| Calculated MW | 6 kDa | 
| Recommended Dilutions | IF 1:200 FC 1:50 | 
| Immunogen | A synthetic peptide corresponding to the sequence of human insulin | 
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. | 
| Synonym | ILPR, IRDN, IDDM2, MODY10, Insulin | 
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