Source: | Rabbit | Gene Id: | 3630 |
Isotype: | IgG | Swiss Prot: | P01308 |
purity: | Affinity purification |
Background: |
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds. Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake. A variety of mutant alleles with changes in the coding region have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. [provided by RefSeq |
Reactivity | Human, Mouse, Rat |
Tested applications | IF FC |
Clonality | Monoclonal Antibody |
Calculated MW | 6 kDa |
Recommended Dilutions |
IF 1:200
FC 1:50
|
Immunogen | A synthetic peptide corresponding to the sequence of human insulin |
Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | ILPR, IRDN, IDDM2, MODY10, Insulin |
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