| Source: | Rabbit | Gene Id: | 5156 | 
| Isotype: | IgG | Swiss Prot: | P16234 | 
| purity: | Affinity purification | 
| Background: | 
| This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes. [provided by RefSeq | 
| Reactivity | Human | 
| Tested applications | IF | 
| Clonality | Monoclonal Antibody | 
| Calculated MW | 190 kDa | 
| Recommended Dilutions | IF 1:50 | 
| Immunogen | A recombinant protein corresponding to the PDGF receptor α extracellular domain | 
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. | 
| Synonym | CD140A, MGC74795, PDGFR2, Rhe-PDGFRA | 
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