Source: | Rabbit | Gene Id: | 9641 |
Isotype: | IgG | Swiss Prot: | Q14164 |
purity: | Affinity purification |
Background: |
IKK epsilon is a noncanonical I-kappa-B kinase (IKK) that is essential for regulating antiviral signaling pathways. It has also been identified as a breast cancer oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (1). IKK epsilon phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. It plays a special role in the immune response. IKK epsilon protects cells against DNA damage-induced cell death (2). |
Reactivity | Human |
Tested applications | WB IP |
Clonality | Monoclonal Antibody |
Calculated MW | 80 kDa |
Recommended Dilutions |
WB 1:1000
|
Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Ser172 of human IKKε protein |
Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | IKBKE, IKK-E, IKK-i, IKKE, IKKI, KIAA0151, MGC125294, MGC125295, MGC125297 |
沪ICP备15003525号 Copyright ©, 2013-2019, Yihyson All Rights Reserved.