Phospho-IKBKE-Ser172 Rabbit Monoclonal Antibody
No Size Price Availability  
ARM9641P-21 50ul 1500.00 In Stock
ARM9641P-21 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 9641
Isotype: IgG Swiss Prot: Q14164
purity: Affinity purification
Background:
IKK epsilon is a noncanonical I-kappa-B kinase (IKK) that is essential for regulating antiviral signaling pathways. It has also been identified as a breast cancer oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (1). IKK epsilon phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. It plays a special role in the immune response. IKK epsilon protects cells against DNA damage-induced cell death (2).
Reactivity Human
Tested applications WB IP
Clonality Monoclonal Antibody
Calculated MW 80 kDa
Recommended Dilutions
WB 1:1000
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser172 of human IKKε protein
Storage Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles.
Synonym IKBKE, IKK-E, IKK-i, IKKE, IKKI, KIAA0151, MGC125294, MGC125295, MGC125297
This product is for research use only, not for diagnostic or therapeutic use!

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