| No | Size | Price | Availability | |
| ARM3630-23C | 50ul | 1500.00 | In Stock |  |
| ARM3630-23C | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 3630 |
| Isotype: | IgG | Swiss Prot: | P01308 |
| purity: | Affinity purification |
| Background: |
| The maintenance of glucose homeostasis is an essential physiological process that is regulated by hormones. An elevation in blood glucose levels during feeding stimulates insulin release from pancreatic β cells through a glucose sensing pathway (1). Insulin is synthesized as a precursor molecule, proinsulin, which is processed prior to secretion. A- and B-peptides are joined together by a disulfide bond to form insulin, while the central portion of the precursor molecule is cleaved and released as the C-peptide. Insulin stimulates glucose uptake from blood into skeletal muscle and adipose tissue. Insulin deficiency leads to type 1 diabetes mellitus (2). |
| Reactivity | Human |
| Tested applications | FC |
| Clonality | Monoclonal Antibody |
| Calculated MW | 6 kDa |
| Recommended Dilutions |
FC 1:50
|
| Immunogen | A synthetic peptide corresponding to the sequence of human insulin |
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | ILPR, IRDN, IDDM2, MODY10, Insulin |
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