Source: | Rabbit | Gene Id: | 57521 |
Isotype: | / | Swiss Prot: | Q8N122 |
purity: | Affinity purification |
Background: |
This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene. |
Reactivity | / |
Tested applications | IP |
Clonality | Monoclonal Antibody |
Calculated MW | 150 kDa |
Recommended Dilutions | |
Immunogen | / |
Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | KOG1, Mip1 |
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