Source: | Mouse | Gene Id: | 3569 |
Isotype: | IgG1 | Swiss Prot: | P05231 |
purity: | Affinity purification |
Background: |
This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. |
Reactivity | Human, Dog, Pig, Cow, Horse, Sheep |
Tested applications | WB IHC ELISA IP IF |
Clonality | Monoclonal Antibody |
Calculated MW | 23 kDa |
Recommended Dilutions |
WB 1:100-1:500
IHC 1:100-1:500
IF 1:100-1:500
|
Immunogen | A synthetic peptide derived from human IL-6 (51-150aa) |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | IL6,BSF2,HGF,HSF,IFNB2,IL-6 |
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