| No | Size | Price | Availability | |
| ARM6416P-21 | 50ul | 1500.00 | In Stock |  |
| ARM6416P-21 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 6416 |
| Isotype: | / | Swiss Prot: | P45985 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants. |
| Reactivity | Human, Monkey, Mouse, Rat |
| Tested applications | WB FC |
| Clonality | Monoclonal Antibody |
| Calculated MW | 44 kDa |
| Recommended Dilutions |
WB 1:1000
FC 1:400
|
| Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Ser257/Thr261 of human SEK1/MKK4 |
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | JNKK, MEK4, MKK4, SEK1, SKK1, JNKK1, SERK1, MAPKK4, PRKMK4, SAPKK1, SAPKK-1 |
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