| No | Size | Price | Availability | |
| ARM6885P-21 | 50ul | 1500.00 | In Stock |  |
| ARM6885P-21 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 6885 |
| Isotype: | IgG | Swiss Prot: | O43318 |
| purity: | Affinity purification |
| Background: |
| The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq |
| Reactivity | Human |
| Tested applications | WB |
| Clonality | Monoclonal Antibody |
| Calculated MW | 82 kDa |
| Recommended Dilutions |
WB 1:1000
|
| Immunogen | A phosphopeptide corresponding to residues surrounding Thr184 and Thr187 of human TAK1 |
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | TAK1, TGF1a |
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