Source: | Rabbit | Gene Id: | 8350 |
Isotype: | IgG | Swiss Prot: | P68431 |
purity: | Affinity purification |
Background: |
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq |
Reactivity | Human, Monkey, Mouse, Rat |
Tested applications | WB |
Clonality | Monoclonal Antibody |
Calculated MW | 17 kDa |
Recommended Dilutions |
WB 1:1000
|
Immunogen | A synthetic peptide corresponding to the amino terminus of histone H3 in which Lys27 is tri-methylated |
Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | H3.4, H3/g, H3FT, H3t, MGC126886, MGC126888 |
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