| No | Size | Price | Availability | |
| AMM5797-11 | 50ul | 1500.00 | In Stock |  |
| AMM5797-11 | 100ul | 2000.00 | In Stock | |
| Source: | Mouse | Gene Id: | 5797 |
| Isotype: | IgG1 Kappa | Swiss Prot: | P28827 |
| purity: | Affinity purification |
| Background: |
| The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms. [provided by RefSeq |
| Reactivity | Human |
| Tested applications | WB IP |
| Clonality | Monoclonal Antibody |
| Calculated MW | 100,110,210 kDa |
| Recommended Dilutions |
WB 1:1000
|
| Immunogen | A recombinant protein corresponding to human PTPRM |
| Storage | Store at -20°C in PBS, pH 7.4 (50% glycerol, 0.09% sodium azide).Avoid freeze/thaw cycles. |
| Synonym | MGC166994, PTPRL1, R-PTP-MU, RPTPM, RPTPU, hR-PTPu |
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