Source: | Mouse | Gene Id: | 4744 |
Isotype: | IgG1 | Swiss Prot: | P12036 |
purity: | Affinity purification |
Background: |
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq |
Reactivity | Bovine |
Tested applications | WB IF |
Clonality | Monoclonal Antibody |
Calculated MW | 180-220 kDa |
Recommended Dilutions |
WB 1:5000
IF 1:500
|
Immunogen | Native purified bovine NEFH |
Storage | Store at -20°C in HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide).Avoid freeze/thaw cycles. |
Synonym | NFH |
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