TYMS Mouse Monoclonal Antibody
No Size Price Availability  
AMM7298-11 50ul 1500.00 In Stock
AMM7298-11 100ul 2000.00 In Stock
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Source: Mouse Gene Id: 7298
Isotype: IgG1 Swiss Prot: P04818
purity: Affinity purification
Background:
Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occuring antisense transcript rTSalpha (GeneID:55556) vary inversely when cell-growth progresses from late-log to plateau phase. [provided by RefSeq
Reactivity Human
Tested applications WB IHC ELISA IP IF FC
Clonality Monoclonal Antibody
Calculated MW 30 kDa
Recommended Dilutions
Immunogen A recombinant protein corresponding to human TYMS
Storage Store at -20°C in PBS (0.08% sodium azide).Avoid freeze/thaw cycles.
Synonym HsT422, MGC88736, TMS, TS, TSase
This product is for research use only, not for diagnostic or therapeutic use!

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