Source: | Mouse | Gene Id: | 6622 |
Isotype: | IgG1 | Swiss Prot: | P37840 |
purity: | Affinity purification |
Background: |
α-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq |
Reactivity | Human |
Tested applications | WB IHC ELISA |
Clonality | Monoclonal Antibody |
Calculated MW | 18 kDa |
Recommended Dilutions | |
Immunogen | A recombinant protein corresponding to human SNCA |
Storage | Store at -20°C in PBS, pH 7.2(0.1% BSA, 0.01% sodium azide).Avoid freeze/thaw cycles. |
Synonym | TLR7-like, MGC110988, NACP, PARK1, PARK4, PD1 |
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