| No | Size | Price | Availability | |
| AMM3099-11 | 50ul | 1500.00 | In Stock |  |
| AMM3099-11 | 100ul | 2000.00 | In Stock | |
| Source: | Mouse | Gene Id: | 3099 |
| Isotype: | IgG1 Kappa | Swiss Prot: | P52789 |
| purity: | Protein G purification |
| Background: |
| Hexokinase catalyzes the conversion of glucose to glucose-6-phosphate, the first step in glycolysis. Four distinct mammalian hexokinase isoforms, designated as hexokinase I, II, III, and IV (glucokinase), have been identified. Hexokinases I, II, and III are associated with the outer mitochondrial membrane and are critical for maintaining an elevated rate of aerobic glycolysis in cancer cells (Warburg Effect) (1) in order to compensate for the increased energy demands associated with rapid cell growth and proliferation (2,3). |
| Reactivity | Human |
| Tested applications | WB ELISA |
| Clonality | Monoclonal Antibody |
| Calculated MW | 102 kDa |
| Recommended Dilutions |
WB 1:1000-1:3000
|
| Immunogen | A recombinant protein corresponding to full length human HK2 |
| Storage | Store at -20°C in PBS, pH 7.4 (0.1% sodium azide).Avoid freeze/thaw cycles. |
| Synonym | HK2, DKFZp686M1669, HKII, HXK2 |
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