ZAP70 Mouse Monoclonal Antibody
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AMM7535-11 50ul 1500.00 In Stock
AMM7535-11 100ul 2000.00 In Stock
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Source: Mouse Gene Id: 7535
Isotype: IgG1 Kappa Swiss Prot: P43403
purity: Affinity purification
Background:
This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.
Reactivity Human
Tested applications WB ELISA IP
Clonality Monoclonal Antibody
Calculated MW 70 kDa
Recommended Dilutions
WB 1:10000
Immunogen A recombinant ABD fusion protein corresponding to amino acids 1-254 of human ZAP70
Storage Store at -20°C in HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide). Avoid freeze/thaw cycles.
Synonym FLJ17670, FLJ17679, SRK, STD, TZK, ZAP-70
This product is for research use only, not for diagnostic or therapeutic use!

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