| No | Size | Price | Availability | |
| AMM5925-13 | 50ul | 1500.00 | In Stock |  |
| AMM5925-13 | 100ul | 2000.00 | In Stock | |
| Source: | Mouse | Gene Id: | 5925 |
| Isotype: | IgG1 Kappa | Swiss Prot: | P06400 |
| purity: | Affinity purification |
| Background: |
| The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. |
| Reactivity | Human |
| Tested applications | WB ELISA IP |
| Clonality | Monoclonal Antibody |
| Calculated MW | 110 kDa |
| Recommended Dilutions |
WB 1:2000
|
| Immunogen | A recombinant protein corresponding to amino acids 701-928 of human RB1 |
| Storage | Store at -20°C in HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide). Avoid freeze/thaw cycles. |
| Synonym | RB, pRb, OSRC, pp110, p105-Rb |
沪ICP备15003525号 Copyright ©, 2013-2019, Yihyson All Rights Reserved. 
