| No | Size | Price | Availability | |
| ARM55851-11 | 50ul | 1500.00 | In Stock |  |
| ARM55851-11 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 55851 |
| Isotype: | IgG | Swiss Prot: | Q9NZ42 |
| purity: | Affinity purification |
| Background: |
| Presenilins, which are components of the gamma-secretase protein complex, are required for intramembranous processing of some type I transmembrane proteins, such as the Notch proteins and the beta-amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta-amyloid precursor protein generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimer's disease. This gene encodes a protein that is required for Notch pathway signaling, and for the activity and accumulation of gamma-secretase. |
| Reactivity | Human |
| Tested applications | WB ELISA |
| Clonality | Monoclonal Antibody |
| Calculated MW | 13 kDa |
| Recommended Dilutions | |
| Immunogen | A synthetic peptide of human PSENEN is used for rabbit immunization |
| Storage | Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles. |
| Synonym | MDS033, MSTP064, PEN-2, PEN2 |
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