AKAP5 Rabbit Monoclonal Antibody
No Size Price Availability  
ARM9495-11 50ul 1500.00 In Stock
ARM9495-11 100ul 2000.00 In Stock
  • Details
  • FAQs
  • Manual
Source: Rabbit Gene Id: 9495
Isotype: IgG Swiss Prot: P24588
purity: Affinity purification
Background:
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT.
Reactivity Human
Tested applications WB ELISA
Clonality Monoclonal Antibody
Calculated MW 79 kDa
Recommended Dilutions
Immunogen A synthetic peptide of human AKAP5 is used for rabbit immunization
Storage Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles.
Synonym AKAP75, AKAP79, H21
This product is for research use only, not for diagnostic or therapeutic use!

backtop
QQ
service center
Contact Us