Source: | Rabbit | Gene Id: | 9459 |
Isotype: | IgG | Swiss Prot: | Q15052 |
purity: | Affinity purification |
Background: |
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific mental retardation. |
Reactivity | Human |
Tested applications | WB ELISA |
Clonality | Monoclonal Antibody |
Calculated MW | 87 kDa |
Recommended Dilutions | |
Immunogen | A synthetic peptide of human ARHGEF6 is used for rabbit immunization |
Storage | Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles. |
Synonym | COOL2, Cool-2, KIAA0006, MRX46, PIXA, alpha-PIX, alphaPIX |
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