| No | Size | Price | Availability | |
| AMM7010-11 | 50ul | 1500.00 | In Stock |  |
| AMM7010-11 | 100ul | 2000.00 | In Stock | |
| Source: | Mouse | Gene Id: | 7010 |
| Isotype: | IgG2a Kappa | Swiss Prot: | Q02763 |
| purity: | Affinity purification |
| Background: |
| The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB ELISA |
| Clonality | Monoclonal Antibody |
| Calculated MW | 160 kDa |
| Recommended Dilutions | |
| Immunogen | TEK (NP_000450, 66 aa ~ 185 aa) partial recombinant protein with GST tag |
| Storage | Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles. |
| Synonym | CD202B, TIE-2, TIE2, VMCM, VMCM1 |
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