TEAD1 Rabbit Monoclonal Antibody
No Size Price Availability  
ARM7003-11 50ul 1500.00 In Stock
ARM7003-11 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 7003
Isotype: IgG Swiss Prot: P28347
purity: Affinity purification
Background:
The Hippo pathway is an important evolutionarily conserved signaling pathway that controls organ size and tumor suppression by inhibiting cell proliferation and promoting apoptosis. An integral function of the Hippo pathway is to repress the activity of Yes-associated protein (YAP), a proposed oncogene whose activity is regulated by phosphorylation and subcellular localization. When the Hippo pathway is turned off, YAP is phosphorylated and translocates to the nucleus where it associates with various transcription factors including members of the transcriptional enhancer factor (TEF) family, also known as the TEA domain (TEAD) family (TEAD1-4). Although widely expressed in tissues, the TEAD family proteins have specific tissue and developmental distributions. YAP/TEAD complexes regulate the expression of genes involved in cell proliferation and apoptosis.
Reactivity Human
Tested applications WB ELISA
Clonality Monoclonal Antibody
Calculated MW 50 kDa
Recommended Dilutions
Immunogen A synthetic peptide of human TEAD1 is used for rabbit immunization
Storage Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles.
Synonym AA, REF1, TCF13, TEF-1
This product is for research use only, not for diagnostic or therapeutic use!

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