PSMB7 Rabbit Monoclonal Antibody
No Size Price Availability  
ARM5695-11 50ul 1500.00 In Stock
ARM5695-11 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 5695
Isotype: IgG Swiss Prot: Q99436
purity: Affinity purification
Background:
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon and proteolytic processing is required to generate a mature subunit. This subunit is not present in the immunoproteasome and is replaced by catalytic subunit 2i (proteasome beta 10 subunit).
Reactivity Human
Tested applications WB ELISA
Clonality Monoclonal Antibody
Calculated MW 28 kDa
Recommended Dilutions
Immunogen A synthetic peptide of human PSMB7 is used for rabbit immunization
Storage Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles.
Synonym Z
This product is for research use only, not for diagnostic or therapeutic use!

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