| No | Size | Price | Availability | |
| AMM4091-61 | 50ul | 1500.00 | In Stock |  |
| AMM4091-61 | 100ul | 2000.00 | In Stock | |
| Source: | Mouse | Gene Id: | 4091 |
| Isotype: | IgG1 | Swiss Prot: | O43541 |
| purity: | Affinity purification |
| Background: |
| Antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit selectively BMP (bone morphogenetic proteins) signaling by competing with the co-SMAD SMAD4 for receptor-activated SMAD1. SMAD6 is an inhibitory SMAD (I-SMAD) or antagonistic SMAD. Binds to regulatory elements in target promoter regions.Tissue specificity: Ubiquitous in various organs, with higher levels in lung. Isoform B is up-regulated in diseased heart tissue. |
| Reactivity | Human |
| Tested applications | WB |
| Clonality | Monoclonal Antibody |
| Calculated MW | 53 kDa |
| Recommended Dilutions |
WB 0.736111
|
| Immunogen | A purified recombinant fragment of human SMAD6 expressed in E. Coli. |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | MADH6, MADH7, HsT17432, SMAD6 |
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