| No | Size | Price | Availability | |
| AMM4089-61 | 50ul | 1500.00 | In Stock |  |
| AMM4089-61 | 100ul | 2000.00 | In Stock | |
| Source: | Mouse | Gene Id: | 4089 |
| Isotype: | IgG1 | Swiss Prot: | Q13485 |
| purity: | Affinity purification |
| Background: |
| Common mediator of signal transduction by TGF-beta (transforming growth factor) superfamily; SMAD4 is the common SMAD (co-SMAD). Promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. May act as a tumor suppressor。Mutations or deletions in this gene have been shown to result in pancreatic cancer, juvenile polyposis syndrome, and hereditary hemorrhagic telangiectasia syndrome. |
| Reactivity | Human, Mouse |
| Tested applications | WB IHC IF |
| Clonality | Monoclonal Antibody |
| Calculated MW | 65 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
IF 0.180556
|
| Immunogen | A purified recombinant fragment of human SMAD4 expressed in E. Coli. |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | JIP, DPC4, MADH4, SMAD4 |
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