Source: | Mouse | Gene Id: | 79135 |
Isotype: | IgG1 | Swiss Prot: | Q9BUR5 |
purity: | Affinity chromatography |
Background: |
ApoO: apolipoprotein O, also known as MYO25, FAM121B, MGC4825. Entrez Protein NP_077027. It is a chrondroitin-sulfate chain containing member of the apolipoprotein family and is an original glycoprotein up-regulated by diabetes in human Heart. Promotes cholesterol efflux from macrophage cells. Detected in HDL, LDL and VLDL. Secreted by a microsomal triglyceride transfer protein (MTTP)-dependent mechanism, probably as a VLDL-associated protein that is subsequently transferred to HDL. May be involved in myocardium-protective mechanisms against lipid accumulation. |
Reactivity | Human, Mouse |
Tested applications | WB IHC ELISA |
Clonality | Monoclonal Antibody |
Calculated MW | 22 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:200-1:1000
|
Immunogen | A purified recombinant fragment of human ApoO expressed in E. Coli |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | Apolipoprotein O [Precursor]Protein FAM121B |
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