AKT2 Mouse Monoclonal Antibody
No Size Price Availability  
AMM208-61 50ul 1500.00 In Stock
AMM208-61 100ul 2000.00 In Stock
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Source: Mouse Gene Id: 208
Isotype: IgG1 Swiss Prot: P31751
purity: Affinity chromatography
Background:
Akt2 (also designated protein kinase B beta or v-akt murine thymoma viral oncogene homolog 2 ), with 481-amino acid protein (about 53kDa), belongs to the AKT serine/threonine protein kinase family, which also includes Akt1 and Akt3. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. Among the members of AKT family, Akt2 is associated with the development of human cancers. Akt2 inhibits cisplatin-induced JNK/p38 and Bax activation through phosphorylation of ASK1 and thus, plays an important role in chemoresistance. Further, Akt2 plays a specific role in muscle differentiation.
Reactivity Human, Monkey, Rat
Tested applications WB IHC ELISA ICC
Clonality Monoclonal Antibody
Calculated MW 60 kDa
Recommended Dilutions
WB 1:500-1:2000
IHC 1:200-1:1000
ICC 1:200-1:1000
Immunogen A purified recombinant fragment of human AKT2 expressed in E. Coli
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym PKBB, PRKBB, PKBBETA, RAC-BETA
This product is for research use only, not for diagnostic or therapeutic use!

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