| No | Size | Price | Availability | |
| AMM6929-61 | 50ul | 1500.00 | In Stock |  |
| AMM6929-61 | 100ul | 2000.00 | In Stock | |
| Source: | Mouse | Gene Id: | 6929 |
| Isotype: | IgG1 | Swiss Prot: | P15923 |
| purity: | Affinity chromatography |
| Background: |
| E2A is a transcription factor that plays major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Heterodimers between E2A and tissue-specific basic helix-loop-helix (bHLH) Dimers bind DNA on E-box motifs: 5'- CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer. Deletions in E2A have been observed in a subset of pre-B-cell acute lymphoblastic leukemia (B-ALL) cases. Two alternatively spliced human isoforms have been described. |
| Reactivity | Human |
| Tested applications | WB ELISA FC |
| Clonality | Monoclonal Antibody |
| Calculated MW | 68 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
FC 1:200-1:400
|
| Immunogen | A purified recombinant fragment of human TCF3 expressed in E. Coli |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | E12, Immunoglobulin enhancer binding factor E12/E47, Immunoglobulin transcription factor-1, ITF1, Kappa-E2-binding factor, TCF-3, TCF3, TFE2, transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47), Transcription factor E2-alpha, Tran |
沪ICP备15003525号 Copyright ©, 2013-2019, Yihyson All Rights Reserved. 
