| No | Size | Price | Availability | |
| AMM6591-61 | 50ul | 1500.00 | In Stock |  |
| AMM6591-61 | 100ul | 2000.00 | In Stock | |
| Source: | Mouse | Gene Id: | 6591 |
| Isotype: | IgG1 | Swiss Prot: | O43623 |
| purity: | Affinity chromatography |
| Background: |
| This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity.The tumor suppressor protein p53 induces Slug expression in gamma-irradiated cells; Slug protects damaged cells from apoptosis by repressing p53-induced transcription of the proapoptotic Bcl-2 family protein Puma. Mutations in this gene may be associated with sporatic cases of neural tube defects. |
| Reactivity | Human |
| Tested applications | WB ELISA |
| Clonality | Monoclonal Antibody |
| Calculated MW | 30 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
|
| Immunogen | A purified recombinant fragment of human SNAI2 expressed in E. Coli |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | SLUG, WS2D, SLUGH1, MGC10182, SNAI2 |
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