Source: | Mouse | Gene Id: | 5591 |
Isotype: | IgG1 | Swiss Prot: | P78527 |
purity: | Affinity chromatography |
Background: |
The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties. |
Reactivity | Human |
Tested applications | WB IHC ELISA ICC |
Clonality | Monoclonal Antibody |
Calculated MW | 450 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:200-1:1000
ICC 1:200-1:1000
|
Immunogen | A purified recombinant fragment of human PRKDC expressed in E. Coli |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | DNA- PKcs, DNA-dependent protein kinase catalytic subunit, DNPK1, EC 2.7.11.1, P460, PRKD, PRKDC, XRCC7, kinase DNA-PK |
沪ICP备15003525号 Copyright ©, 2013-2019, Yihyson All Rights Reserved.