CCND3 Mouse Monoclonal Antibody
No Size Price Availability  
AMM896-61 50ul 1500.00 In Stock
AMM896-61 100ul 2000.00 In Stock
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Source: Mouse Gene Id: 896
Isotype: IgG1 Swiss Prot: P30281
purity: Affinity chromatography
Background:
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene.
Reactivity Human, Mouse
Tested applications WB ELISA
Clonality Monoclonal Antibody
Calculated MW 32 kDa
Recommended Dilutions
WB 1:500-1:2000
Immunogen A purified recombinant fragment of human CCND3 expressed in E. Coli
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym /
This product is for research use only, not for diagnostic or therapeutic use!

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