| No | Size | Price | Availability | |
| AMM4312-61 | 50ul | 1500.00 | In Stock |  |
| AMM4312-61 | 100ul | 2000.00 | In Stock | |
| Source: | Mouse | Gene Id: | 4312 |
| Isotype: | IgG1 | Swiss Prot: | P03956 |
| purity: | Affinity chromatography |
| Background: |
| Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants. |
| Reactivity | Human |
| Tested applications | WB IHC ELISA ICC FC |
| Clonality | Monoclonal Antibody |
| Calculated MW | 54 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:200-1:1000
ICC 1:200-1:1000
FC 1:200-1:400
|
| Immunogen | A purified recombinant fragment of human MMP1 expressed in E. Coli |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | EC 3.4.24.7Matrix metalloproteinase-1MMP1Fibroblast collagenase |
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