WDR5 Mouse Monoclonal Antibody
No Size Price Availability  
AMM11091-61 50ul 1500.00 In Stock
AMM11091-61 100ul 2000.00 In Stock
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Source: Mouse Gene Id: 11091
Isotype: IgG1 Swiss Prot: P61964
purity: Affinity chromatography
Background:
WD-repeat protein 5 (WDR5, also designated BMP-2-induced gene 3 kb or BIG-3) belongs to the family of WD-40 repeat proteins, and is essential for vertebrate development, Hox gene activation and global H3K4 trimethylation. WDR5 is a conserved subunit of Trithorax (TRX) histone methyltransferase complexes that selectively binds to dimethylated Lys4 (K4me2) in Histone H3 to promote K4 trimethylation by TRX. It is expressed in osteoblasts, chondrocytes, osteocytes and marrow stromal cells. The WDR5 protein contains 7 WD-repeats, which may play a role in its function of accelerating osteoblast differentiation.
Reactivity Human
Tested applications WB ELISA
Clonality Monoclonal Antibody
Calculated MW 37 kDa
Recommended Dilutions
WB 1:500-1:2000
Immunogen A purified recombinant fragment of human WDR5 expressed in E. Coli
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym SWD3, BIG-3, WDR5
This product is for research use only, not for diagnostic or therapeutic use!

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