CTCF Mouse Monoclonal Antibody
No Size Price Availability  
AMM10664-61 50ul 1500.00 In Stock
AMM10664-61 100ul 2000.00 In Stock
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Source: Mouse Gene Id: 10664
Isotype: IgG1 Swiss Prot: P49711
purity: Affinity chromatography
Background:
This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors.Tissue specificity: Ubiquitous. Absent in primary spermatocytes.
Reactivity Human, Monkey
Tested applications WB ELISA
Clonality Monoclonal Antibody
Calculated MW 83 kDa
Recommended Dilutions
WB 1:500-1:2000
Immunogen A purified recombinant fragment of human CTCF expressed in E. Coli
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym CTCF
This product is for research use only, not for diagnostic or therapeutic use!

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