Source: | Mouse | Gene Id: | 943 |
Isotype: | IgG1 | Swiss Prot: | P28908 |
purity: | Affinity chromatography |
Background: |
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
Reactivity | Human |
Tested applications | WB ELISA FC |
Clonality | Monoclonal Antibody |
Calculated MW | 64 kDa |
Recommended Dilutions |
WB 1:500-1:2000
FC 1:200-1:400
|
Immunogen | A purified recombinant fragment of human CD30 expressed in E. Coli |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | CD30, Ki-1, D1S166E, TNFRSF8 |
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