Source: | Mouse | Gene Id: | 3852 |
Isotype: | IgG1 | Swiss Prot: | P13647 |
purity: | Affinity chromatography |
Background: |
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. |
Reactivity | Human, Monkey, Mouse |
Tested applications | WB IHC ELISA ICC FC |
Clonality | Monoclonal Antibody |
Calculated MW | 62 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:200-1:1000
ICC 1:200-1:1000
FC 1:200-1:400
|
Immunogen | A purified recombinant fragment of human CK5 expressed in E. Coli |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | KRT5, K5, DDD, EBS2, KRT5A |
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