Source: | Mouse | Gene Id: | 5967 |
Isotype: | IgG1 | Swiss Prot: | P05451 |
purity: | Affinity chromatography |
Background: |
REG1A (regenerating islet-derived 1 alpha), also known as PTP, PSP, is a member of the Reg family of secreted proteins with a C-type lectin domain. REG1A is associated with islet cell regeneration and diabetogenesis and may be involved in pancreatic lithogenesis.Due to variable glycosylation, pancreatic REG1A exists as multiple species of 16 - 18 kDa. REG1A promotes the maintenance and growth of pancreatic islet beta-cells and intestinal villi. It is upregulated in pancreatitis and some carcinomas. REG1A is an antigenic target in autoimmune diabetes. |
Reactivity | Human |
Tested applications | IHC ELISA ICC |
Clonality | Monoclonal Antibody |
Calculated MW | 19 kDa |
Recommended Dilutions |
IHC 1:200-1:1000
ICC 1:200-1:1000
|
Immunogen | A purified recombinant fragment of human REG1A expressed in E. Coli |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | P19, PTP, PSP |
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